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[59] Agents associated with a moderately increased risk include nonsteroidal anti-inflammatory drugs (such as ibuprofen), bisphosphonates, and other chemotherapeutic agents such as melphalan, interleukin-2, and anthracyclines

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Chapter: 3 3.1 Methodology Systematic Review is the organized methodology of systematically scrutinizing and speculating the varied different intervention evaluations which in these regards are done here following the Cochrane Collaboration format by formulating in the form of: Systematizing a clinical issue Identifying and isolating selective studies Critical analysis and assessment of studies Congregating valuable information and databanks Assaying, analyzing and apprising the outcome Elaborating and elucidating the results Developing improved reviews 3.1 Selection Criteria 3.1.1 Inclusion Criteria Credible studies published in English particularly those sponsored and funded by government health organizations